Isabella Restaurant and Bar is located at 1140 Route 315 in Wilkes-Barre, Pennsylvania.
From 81 South:Take 81 South to the Pittston Exit (Exit 175A). Travel 315 South approximately 5 miles to Isabella.
From the Cross Valley:Take the Cross Valley Expressway to Exit 1. Turn left onto Rte. 315 and travel approximately 2 miles to Isabella.